SCHEMBL7248010

SCHEMBL7248010

C/C=C(/CC(F)(F)F)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 3/20 0.40
GRIK2 Q13002 2/20 0.40
ABAT P80404 1/20 0.33
TET2 Q6N021 2/20 0.32
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.31
PLA2G4A P47712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2121629 1.00 GRIK1 (0.40) GRIK1GRIK2ABATTET2KDM4E
SCHEMBL2120625 0.81 GRIK1 (0.38) GRIK1GRIK2ABATTET2
SCHEMBL28126621 0.78 GRIK1 (0.30) GRIK1GRIK2PLA2G4A
SCHEMBL845018 0.78 ABAT (0.32) ABATKDM4ETSHR
SCHEMBL845019 0.78 ABAT (0.32) ABATKDM4ETSHR
SCHEMBL6709352 0.78 KDM4E (0.50) ABATKDM4ETSHR
SCHEMBL2422029 0.78 GRIK1 (0.35) GRIK1GRIK2TET2
SCHEMBL7252430 0.78 GRIK1 (0.39) GRIK1GRIK2
SCHEMBL7252434 0.78 GRIK1 (0.39) GRIK1GRIK2
SCHEMBL7976834 0.77 GRIK1 (0.41) GRIK1GRIK2ABATTET2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6632372-B1 Method of forming via-holes in multilayer circuit boards INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2003-10-14 US disclosed