SCHEMBL845019

SCHEMBL845019

O=C(O)C(=CCl)CC(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ABAT P80404 1/20 0.32
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL845018 1.00 ABAT (0.32) ABATKDM4ETSHR
SCHEMBL7861433 0.78 TSHR (0.31) KDM4ETSHR
SCHEMBL2121629 0.78 GRIK1 (0.40) ABATKDM4ETSHR
SCHEMBL7861434 0.78 TSHR (0.31) KDM4ETSHR
SCHEMBL7248010 0.78 GRIK1 (0.40) ABATKDM4ETSHR
SCHEMBL6709352 0.76 KDM4E (0.50) ABATKDM4ETSHR
SCHEMBL9714949 0.73 ALDH1A1 (0.35) ABATKDM4ETSHR
SCHEMBL383865 0.69
SCHEMBL13233298 0.69
SCHEMBL9346923 0.68 ABAT (0.34) ABATTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815273-B2 Drug eluting medical devices having porous layers BOSTON SCIENTIFIC SCIMED, INC. (US) 2014-08-26 US claimed
EP-2175903-B1 DRUG ELUTING MEDICAL DEVICES HAVING POROUS LAYERS BOSTON SCIENT SCIMED INC (US) 2012-03-28 EP claimed
EP-2175903-A2 DRUG ELUTING MEDICAL DEVICES HAVING POROUS LAYERS Boston Scientific Scimed, Inc. (US) 2010-04-21 EP claimed
WO-2009018035-A2 DRUG ELUTING MEDICAL DEVICES HAVING POROUS LAYERS BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-02-05 WO claimed
US-20090029077-A1 Drug eluting medical devices having porous layers BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-01-29 US claimed
US-8815273-B2 Drug eluting medical devices having porous layers BOSTON SCIENTIFIC SCIMED, INC. (US) 2014-08-26 US disclosed
EP-2175903-B1 DRUG ELUTING MEDICAL DEVICES HAVING POROUS LAYERS BOSTON SCIENT SCIMED INC (US) 2012-03-28 EP disclosed
EP-2175903-A2 DRUG ELUTING MEDICAL DEVICES HAVING POROUS LAYERS Boston Scientific Scimed, Inc. (US) 2010-04-21 EP disclosed
EP-1782049-A4 CAPILLARY ELECTROPHORESIS DEVICES AND PROCESSES FOR MANUFACTURING SAME AST MAN INC (WS) 2009-02-25 EP disclosed
WO-2009018035-A2 DRUG ELUTING MEDICAL DEVICES HAVING POROUS LAYERS BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-02-05 WO disclosed
US-20090029077-A1 Drug eluting medical devices having porous layers BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-01-29 US disclosed
EP-1782049-A2 CAPILLARY ELECTROPHORESIS DEVICES AND PROCESSES FOR MANUFACTURING SAME AST Management Inc. (WS) 2007-05-09 EP disclosed
US-7211184-B2 Capillary electrophoresis devices AST MANAGEMENT INC. (WS) 2007-05-01 US disclosed
WO-2006022810-A2 CAPILLARY ELECTROPHORESIS DEVICES AST MANAGEMENT INC. (WS) 2006-03-02 WO disclosed
US-20060027458-A1 Capillary electrophoresis devices and processes for manufacturing same AST MANAGEMENT INC. (WS) 2006-02-09 US disclosed
US-4717645-A LITHOGRAPHY, SEMICONDUCTORS, BAKING, COOLING, DEVELOPMENT TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) 1988-01-05 US disclosed