Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CTH | P32929 | 1/20 | 0.38 |
| ▸ | CBS | P35520 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CD69 | Q07108 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875863 | 0.88 | TSHR (0.33) | TSHRCTHCBSTHPOSMN1; SMN2 | |
| SCHEMBL10287431 | 0.88 | PTGS1 (0.35) | TSHRCTHCBSTHPOSMN1; SMN2 | |
| SCHEMBL18636078 | 0.86 | PTGS1 (0.34) | TSHRCTHCBSTHPOSMN1; SMN2 | |
| SCHEMBL703051 | 0.84 | TSHR (0.38) | TSHRCTHCBSTHPOSMN1; SMN2 | |
| SCHEMBL24442271 | 0.82 | TSHR (0.31) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL24442121 | 0.82 | TSHR (0.31) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL24441364 | 0.82 | TSHR (0.31) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL9487865 | 0.80 | TSHR (0.40) | TSHRCTHCBSTHPOSMN1; SMN2 | |
| SCHEMBL31232468 | 0.80 | ALDH1A1 (0.32) | ELANEALDH1A1 | |
| SCHEMBL20908742 | 0.80 | PAM (0.42) | TSHRHSD17B10FFAR1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4219672-A | Ether carboxylic acids | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1980-08-26 | — | — | US | claimed |
| EP-1541700-B1 | METHOD OF GRANULATING SINTERING MATERIAL FOR IRON MANUFACTURING | NIPPON STEEL CORP (JP) | 2012-02-29 | — | — | EP | disclosed |
| EP-1541700-A1 | METHOD OF GRANULATING SINTERING MATERIAL FOR IRON MANUFACTURING | NIPPON STEEL CORPORATION (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-4219672-A | Ether carboxylic acids | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1980-08-26 | — | — | US | disclosed |
| US-4153726-A | Skin protection agents containing polyethercarboxylic acids | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1979-05-08 | — | — | US | disclosed |