Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.55 |
| ▸ | PPARG | P37231 | 4/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7251593 | 1.00 | PPARA (0.55) | PPARAPPARGPPARDNR1H4MEN1 | |
| SCHEMBL7243669 | 0.92 | PPARA (0.54) | PPARAPPARGPPARDNR1H4MEN1 | |
| SCHEMBL7243667 | 0.92 | PPARA (0.54) | PPARAPPARGPPARDNR1H4MEN1 | |
| SCHEMBL6003755 | 0.92 | PPARA (0.57) | PPARAPPARGPPARDNR1H4MEN1 | |
| SCHEMBL6003752 | 0.92 | PPARA (0.57) | PPARAPPARGPPARDNR1H4MEN1 | |
| SCHEMBL6004647 | 0.92 | PPARA (0.57) | PPARAPPARGPPARDNR1H4MEN1 | |
| SCHEMBL14265701 | 0.86 | MEN1 (0.52) | PPARAPPARGMEN1KMT2APOLB | |
| SCHEMBL14265693 | 0.81 | MAPT (0.46) | PPARAPPARGNR1H4KMT2APOLB | |
| Alcohol SCHEMBL7257570 | 0.79 | PPARA (0.56) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL7530767 | 0.79 | MEN1 (0.52) | PPARAPPARGMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608194-B1 | Hypolipidemic, antihyperglycemic, antiobesity and hypocholes-terolemic agents | DR. REDDY'S LABORATORIES LIMITED (IN) | 2003-08-19 | — | — | US | disclosed |