Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.57 |
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003752 | 1.00 | PPARA (0.57) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL6004647 | 1.00 | PPARA (0.57) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL7251593 | 0.92 | PPARA (0.55) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL7249198 | 0.92 | PPARA (0.55) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL7243669 | 0.88 | PPARA (0.54) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL7243667 | 0.88 | PPARA (0.54) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5112991 | 0.86 | MEN1 (0.52) | PPARAPPARGMEN1KMT2APOLB | |
| SCHEMBL5112985 | 0.86 | MEN1 (0.52) | PPARAPPARGMEN1KMT2APOLB | |
| SCHEMBL7530767 | 0.86 | MEN1 (0.52) | PPARAPPARGMEN1KMT2APOLB | |
| SCHEMBL7243645 | 0.85 | POLB (0.46) | PPARAPPARGMEN1KMT2ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002537390-A | — | — | 2002-11-05 | — | — | JP | claimed |
| US-6440961-B1 | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-08-27 | — | — | US | claimed |
| US-20020077320-A1 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION AND REDDY- CHEMINOR, INC. | 2002-06-20 | — | — | US | claimed |
| EP-1155006-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Dr. Reddy's Research Foundation (IN) | 2001-11-21 | — | — | EP | claimed |
| EP-1049684-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-08 | — | — | EP | claimed |
| WO-2000050414-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | DR.REDDY'S RESEARCH FOUNDATION (IN) | 2000-08-31 | — | — | WO | claimed |
| WO-1999019313-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-04-22 | — | — | WO | claimed |
| US-7119198-B2 | Tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2006-10-10 | — | — | US | disclosed |
| US-20060148793-A1 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | REDDYS'S RESEARCH FOUNDATION | 2006-07-06 | — | — | US | disclosed |
| US-6939988-B1 | Tricyclic compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2005-09-06 | — | — | US | disclosed |
| US-6440961-B1 | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-08-27 | — | — | US | disclosed |
| US-20020077320-A1 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION AND REDDY- CHEMINOR, INC. | 2002-06-20 | — | — | US | disclosed |
| EP-1155006-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Dr. Reddy's Research Foundation (IN) | 2001-11-21 | — | — | EP | disclosed |
| EP-1049684-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-08 | — | — | EP | disclosed |
| WO-2000050414-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | DR.REDDY'S RESEARCH FOUNDATION (IN) | 2000-08-31 | — | — | WO | disclosed |
| US-6054453-A | HYPOLIPIDEMIC, ANTIHYPERGLYCEMIC USES. | REDD'S RESEARCH FOUNDATION (IN) | 2000-04-25 | — | — | US | disclosed |
| WO-1999019313-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077320-A1 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | LIPC, GPR119, CPT1A | PPARA 281/4885PPARG 102/4885PPARD 308/4885 |
| US-20060148793-A1 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | LIPC, GPR119, CPT1A | PPARA 209/4885PPARG 73/4885PPARD 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.