Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.59 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.59 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.59 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.59 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.42 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7249222 | 1.00 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2CYSLTR1 | |
| SCHEMBL7248193 | 0.86 | PTGER1 (0.66) | PTGER1PTGER4PTGER3PTGER2CYSLTR1 | |
| SCHEMBL7248196 | 0.86 | PTGER1 (0.66) | PTGER1PTGER4PTGER3PTGER2CYSLTR1 | |
| SCHEMBL7248194 | 0.86 | PTGER1 (0.66) | PTGER1PTGER4PTGER3PTGER2CYSLTR1 | |
| SCHEMBL919524 | 0.81 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL30530488 | 0.81 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL919522 | 0.81 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL8334320 | 0.80 | MEN1 (0.51) | CYSLTR1CYSLTR2MEN1KMT2A | |
| SCHEMBL13513030 | 0.80 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL6750524 | 0.77 | KDM4E (0.67) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627656-B2 | Antagonists of the pain and inflammatory effects of E-type prostaglandins administered alone or in combination with analgesics, antipyretics, NSAIDs, antitussives, decongestants etc | MERCK FROSST CANADA LTD. (CA) | 2003-09-30 | — | — | US | disclosed |
| US-20020082266-A1 | Method of treatment using phenyl and biaryl derivatives as prostaglandin E inhibitors and compounds useful therefore | MERCK FROSST CANADA LTD. (CA) | 2002-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082266-A1 | Method of treatment using phenyl and biaryl derivatives as prostaglandin E inhibitors and compounds useful therefore | PTGER1, PTGS1, PTGES | PTGER1 1/4885PTGER4 12/4885PTGER3 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.