Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293275 | 0.85 | NPSR1 (0.46) | NPSR1ALDH1A1HTTMAPTTHRB | |
| SCHEMBL6671813 | 0.84 | NPSR1 (0.44) | NPSR1ALDH1A1HTTMAPTTDP1 | |
| SCHEMBL6929857 | 0.84 | NPSR1 (0.44) | NPSR1ALDH1A1HTTMAPTTDP1 | |
| SCHEMBL4921605 | 0.83 | NPSR1 (0.43) | NPSR1ALDH1A1HTTMAPTTDP1 | |
| SCHEMBL28096823 | 0.83 | NPSR1 (0.43) | NPSR1ALDH1A1HTTMAPTTDP1 | |
| SCHEMBL27986058 | 0.82 | NPSR1 (0.43) | NPSR1ALDH1A1HTTMAPTTDP1 | |
| SCHEMBL3154313 | 0.79 | THRB (0.44) | NPSR1ALDH1A1MAPTTHRBTSHR | |
| SCHEMBL19717778 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HTTTSHR | |
| SCHEMBL4737915 | 0.77 | MAPT (0.44) | ALDH1A1MAPTTSHRTDP1HSD17B10 | |
| SCHEMBL4737907 | 0.77 | MAPT (0.44) | ALDH1A1MAPTTSHRTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104487431-B | Treat and prevent the new indazole compounds of respiratory syncytial virus infection | 弗·哈夫曼-拉罗切有限公司 | 2017-06-09 | — | — | CN | disclosed |
| US-6630598-B2 | Reacting nitroaniline compound with acid chloride/anhydride in presence of alkali metal/earth metal compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-10-07 | — | — | US | disclosed |