Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | PROC | P04070 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.40 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7249313 | 1.00 | F2 (0.53) | F2HDAC1HDAC8BCHEACHE | |
| SCHEMBL7249444 | 0.88 | F2 (0.64) | F2SLC22A2F10PLGPLAT | |
| SCHEMBL7249442 | 0.88 | F2 (0.64) | F2SLC22A2F10PLGPLAT | |
| Hydrochloric Acid SCHEMBL7243577 | 0.83 | F2 (0.66) | F2SLC22A2F10PLGPLAT | |
| SCHEMBL7243857 | 0.81 | F2 (0.54) | F2HDAC1HDAC8HDAC6 | |
| SCHEMBL7245089 | 0.80 | F2 (0.52) | F2HDAC1HDAC8HDAC6CNR1 | |
| SCHEMBL7245210 | 0.78 | F2 (0.51) | F2HDAC1HDAC8BCHEACHE | |
| Hydrochloric Acid SCHEMBL7252298 | 0.77 | F2 (0.65) | F2SLC22A2F10PLGPLAT | |
| SCHEMBL7245849 | 0.75 | F2 (0.60) | F2SLC22A2F10PLGPLAT | |
| SCHEMBL7245848 | 0.75 | F2 (0.60) | F2SLC22A2F10PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512000-B1 | Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-01-28 | — | — | US | disclosed |