SCHEMBL7249357

SCHEMBL7249357

CC1(C)OB(c2ccc(CBr)cc2B2OC(C)(C)C(C)(C)O2)OC1(C)C

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 11/20 0.42
LPL P06858 10/20 0.42
F11 P03951 1/20 0.37
ESR2 Q92731 1/20 0.35
UCHL1 P09936 1/20 0.32
ANPEP P15144 1/20 0.30
LAP3 P28838 1/20 0.30
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14696743 0.86 LPL (0.40) LIPGLPLF11ESR2UCHL1
SCHEMBL22982573 0.85 LPL (0.39) LIPGLPLF11ESR2UCHL1
SCHEMBL29531067 0.85 LPL (0.39) LIPGLPLF11ESR2UCHL1
SCHEMBL258023 0.85 LPL (0.39) LIPGLPLF11ESR2UCHL1
SCHEMBL14694384 0.82 LPL (0.37) LIPGLPLF11UCHL1
SCHEMBL7248939 0.82 LIPG (0.42) LIPGLPLF11ESR2UCHL1
SCHEMBL104247 0.76 LPL (0.65) LIPGLPLF11ESR2
SCHEMBL3039403 0.74 LIPG (0.63) LIPGLPLF11ESR2ANPEP
SCHEMBL14696474 0.74 LIPG (0.41) LIPGLPLF11
SCHEMBL1075777 0.73 LPL (0.41) LIPGLPLF11ESR2P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6630577-B2 Useful for producing bioconjugates PROLINX, INC. 2003-10-07 US disclosed
EP-1264833-A2 1,2-Phenylenediboronic acid reagents and complexes PROLINX, INC. (US) 2002-12-11 EP disclosed
US-20020038004-A1 1,2-phenylenediboronic acid reagents and complexes PROLINX, INC. 2002-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020038004-A1 1,2-phenylenediboronic acid reagents and complexes BCR, MGST1, SULT1E1 LIPG 3653/4885LPL 4435/4885F11 587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.