Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7256031 | 0.89 | F2 (0.44) | F2HDAC1HDAC8NTRK1HDAC6 | |
| SCHEMBL6486632 | 0.82 | F2 (0.50) | F2HDAC1HDAC8GLP1RNTRK1 | |
| SCHEMBL7248938 | 0.82 | HTR2C (0.43) | F2HDAC1HDAC8GLP1RNTRK1 | |
| Hydrochloric Acid SCHEMBL7244675 | 0.81 | F2 (0.49) | F2HDAC1HDAC8GLP1RNTRK1 | |
| SCHEMBL7250650 | 0.76 | GLP1R (0.48) | F2HDAC1HDAC8GLP1RHDAC6 | |
| Phenylpiperazine SCHEMBL7248311 | 0.75 | HTR2C (0.46) | F2HDAC1HDAC8GLP1RNTRK1 | |
| SCHEMBL7244672 | 0.74 | F2 (0.47) | F2HDAC1HDAC8NTRK1HDAC6 | |
| SCHEMBL7246014 | 0.74 | HDAC1 (0.50) | F2HDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL6475543 | 0.72 | KDM4E (0.48) | F2HDAC1HDAC8NTRK1HDAC6 | |
| SCHEMBL7255958 | 0.72 | GLP1R (0.43) | F2HDAC1HDAC8GLP1RNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512000-B1 | Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-01-28 | — | — | US | disclosed |