Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256400 | 0.84 | ADORA2A (0.44) | ADORA2AADORA1GABRA1GABRG2GABRB3 | |
| SCHEMBL5553184 | 0.83 | ADORA2A (0.49) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL7953446 | 0.82 | KMT2A (0.50) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL8569411 | 0.80 | ADORA2A (0.41) | ADORA2AADORA1KMT2AALDH1A1HDAC4 | |
| SCHEMBL8571130 | 0.80 | ADORA2A (0.41) | ADORA2AADORA1GABRA1GABRG2GABRB3 | |
| SCHEMBL7249245 | 0.79 | GAA (0.41) | GABRA1GABRG2GABRB3GABRA3KMT2A | |
| SCHEMBL6613269 | 0.79 | ADORA2A (0.46) | ADORA2AADORA1KMT2AALDH1A1TGFBR1 | |
| SCHEMBL6613296 | 0.79 | ADORA2A (0.48) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL7245294 | 0.78 | SCN9A (0.40) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL8571955 | 0.78 | ADORA2A (0.39) | ADORA2AADORA1GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528456-B2 | Selectivity, desirable rate of degradation in soil | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-04 | — | — | US | disclosed |
| US-20020137633-A1 | Herbicidal 2-pyrazolyl-6-aryloxypyri(mi)dines | BASF AKTIENEGESELLSCHAFT (DE) | 2002-09-26 | — | — | US | disclosed |
| EP-1108720-A9 | Herbicidal 2-Pyrazolyl-6-Aryloxy-Pyri(mi)dines | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-31 | — | — | EP | disclosed |
| EP-1108720-A1 | Herbicidal 2-Pyrazolyl-6-Aryloxy-Pyri(mi)dines | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137633-A1 | Herbicidal 2-pyrazolyl-6-aryloxypyri(mi)dines | DDT, CYP4X1, PRDX6 | ADORA2A 2349/4885ADORA1 747/4885GABRA1 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.