Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.37 |
| ▸ | KCNT1 | Q5JUK3 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571130 | 0.80 | ADORA2A (0.41) | ADORA2AADORA1KMT2AKCNT1ALDH1A1 | |
| SCHEMBL7250243 | 0.80 | ADORA2A (0.46) | ADORA2AADORA1HDAC6HDAC1HDAC8 | |
| SCHEMBL8571955 | 0.78 | ADORA2A (0.39) | ADORA2AADORA1KMT2AKCNT1ALDH1A1 | |
| SCHEMBL7256400 | 0.77 | ADORA2A (0.44) | ADORA2AADORA1KMT2AALDH1A1 | |
| SCHEMBL5553184 | 0.76 | ADORA2A (0.49) | ADORA2AADORA1KMT2AALDH1A1 | |
| SCHEMBL7953446 | 0.75 | KMT2A (0.50) | ADORA2AADORA1HDAC6HDAC1HDAC8 | |
| SCHEMBL6613296 | 0.72 | ADORA2A (0.48) | ADORA2AADORA1KMT2AALDH1A1 | |
| SCHEMBL6613269 | 0.72 | ADORA2A (0.46) | ADORA2AADORA1KMT2AALDH1A1 | |
| SCHEMBL5140048 | 0.72 | KDM4E (0.45) | ADORA2AADORA1KMT2AALDH1A1 | |
| SCHEMBL6613579 | 0.71 | ADORA2A (0.47) | ADORA2AADORA1KMT2AKCNT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750470-A | Herbicidal 2,6-disubstituted pyridine compounds and compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-12 | — | — | US | disclosed |