Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019717 | 0.88 | L3MBTL1 (0.39) | KMT2AADORA2AADORA1L3MBTL1MAPT | |
| SCHEMBL5553184 | 0.85 | ADORA2A (0.49) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL7250243 | 0.82 | ADORA2A (0.46) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL5553159 | 0.81 | KMT2A (0.50) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL6613269 | 0.81 | ADORA2A (0.46) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL6613296 | 0.81 | ADORA2A (0.48) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL6613579 | 0.80 | ADORA2A (0.47) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL9098676 | 0.80 | MAPT (0.51) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL8629274 | 0.80 | KMT2A (0.46) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 | |
| SCHEMBL8574398 | 0.80 | ADORA2A (0.50) | KMT2AADORA2AADORA1ALDH1A1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806415-B1 | Process for the preparation of arylamides of heteroaromatic carboxylic acids | LONZA AG (CH) | 2000-02-16 | — | — | EP | claimed |
| EP-0806415-A1 | Process for the preparation of arylamides of heteroaromatic carboxylic acids | LONZA AG (CH) | 1997-11-12 | — | — | EP | claimed |
| JP-10059964-A | — | — | None | — | — | JP | disclosed |
| US-6271372-B1 | REACTING HETEROAROMATIC HALOGEN COMPOUNDS WITH CARBON MONOXIDE AND AROMATIC AMINES IN THE PRESENCE OF A COMPLEX OF PALLADIUM WITH A TRIPHENYLPHOSPHINE AND A BASE OTHER THAN AN AMINE. | LONZA AG (CH) | 2001-08-07 | — | — | US | disclosed |
| EP-0806415-B1 | Process for the preparation of arylamides of heteroaromatic carboxylic acids | LONZA AG (CH) | 2000-02-16 | — | — | EP | disclosed |
| US-5900484-A | FROM HETEROAROMATIC HALOGEN COMPOUNDS AND AROMATIC AMINES AND CARBON MONOXIDE WITH PALLADIUM PHOSPHINE COMPLEX | LONZA AG (CH) | 1999-05-04 | — | — | US | disclosed |
| US-5892032-A | Process for the preparation of arylamides of heteroaromatic carboxylic acids | LONZA AG (CH) | 1999-04-06 | — | — | US | disclosed |
| JP-H1059964-A | PRODUCTION OF ARYLAMIDE OF HETEROCYCLIC AROMATIC CARBOXYLIC ACID | LONZA AG | 1998-03-03 | — | — | JP | disclosed |
| EP-0806415-A1 | Process for the preparation of arylamides of heteroaromatic carboxylic acids | LONZA AG (CH) | 1997-11-12 | — | — | EP | disclosed |