Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1470290 | 0.88 | TSHR (0.52) | TSHRCYP4F2CYP4A11CA12CA1 | |
| SCHEMBL7703503 | 0.84 | FFAR4 (0.45) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL13870603 | 0.84 | CYP4F2 (0.51) | TSHRCYP4F2CYP4A11CA12CA1 | |
| SCHEMBL1702411 | 0.83 | CYP4F2 (0.66) | TSHRCYP4F2CYP4A11CA12CA1 | |
| SCHEMBL5238335 | 0.83 | SMN1; SMN2 (0.51) | TSHRCYP4F2CYP4A11CA12CA1 | |
| SCHEMBL4628672 | 0.82 | TSHR (0.60) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL5250038 | 0.81 | CYP4F2 (0.56) | TSHRCYP4F2CYP4A11CA12CA1 | |
| SCHEMBL14941222 | 0.81 | TSHR (0.50) | TSHRCYP4F2CYP4A11CA12CA1 | |
| SCHEMBL5777608 | 0.81 | TSHR (0.55) | TSHRCYP4F2CYP4A11CA12CA1 | |
| SCHEMBL5405115 | 0.81 | MRGPRX4 (0.48) | TSHRCYP4F2CYP4A11CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023029943-A1 | AROMATIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 星药科技(北京)有限公司 | 2023-03-09 | — | — | WO | disclosed |
| CN-111057074-B | Inhibitors of influenza virus replication and uses thereof | 广东东阳光药业有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-111057074-A | Inhibitors of influenza virus replication and uses thereof | 广东东阳光药业有限公司 | 2020-04-24 | — | — | CN | disclosed |
| US-7524864-B2 | Methods of treating sleep disorders | HYPNION, INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-7524864-B2 | Methods of treating sleep disorders | HYPNION, INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-20030216571-A1 | Antiallergens; antiinflammatory agents | UBE INDUSTRIES, LTD. (JP) | 2003-11-20 | — | — | US | disclosed |
| EP-1254897-A1 | TRICYCLIC COMPOUNDS | Ube Industries, Ltd. (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-4816591-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| US-4585788-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| US-4082850-A | TOPICAL APPLICATION OF A 6,11-DIHYDROBENZ(B,E)OXEPIN-ALKANOIC ACID OR DERIVATIVES THEREOF | AMERICAN HOECHST CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216571-A1 | Antiallergens; antiinflammatory agents | CYSLTR2, CYSLTR1, LTC4S | TSHR 4253/4885CYP4F2 2431/4885CYP4A11 767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.