Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27472374 | 0.89 | MRGPRX4 (0.47) | MRGPRX4CYP4F2CYP4A11CFTRCA12 | |
| SCHEMBL10565429 | 0.89 | MRGPRX4 (0.48) | MRGPRX4CYP4F2CYP4A11CFTRCA12 | |
| SCHEMBL162621 | 0.87 | CYP4F2 (0.47) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL5833870 | 0.85 | CFTR (0.61) | MRGPRX4CFTRCA12CA1CA2 | |
| SCHEMBL4691963 | 0.83 | CA12 (0.50) | MRGPRX4CFTRCA12CA1CA2 | |
| SCHEMBL8997654 | 0.82 | MRGPRX4 (0.47) | MRGPRX4CFTRCA12CA1CA2 | |
| SCHEMBL1998616 | 0.81 | CES2 (0.60) | MRGPRX4CFTRCA12CA1CA2 | |
| SCHEMBL7250264 | 0.81 | TSHR (0.52) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL5943406 | 0.81 | CA12 (0.64) | MRGPRX4CFTRCA12CA1CA2 | |
| SCHEMBL28195998 | 0.81 | MRGPRX4 (0.48) | MRGPRX4CFTRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260132149-A1 | Bridged Cyclic 5-Amino-6,8-Dihydro-1H-Furo[3,4-D]Pyrrolo[3,2-B]Pyridine-2-Carboxamide Compounds, Compositions Thereof, and Methods of Treatment Therewith | BEONE MEDICINES I GMBH (CH) | 2026-05-14 | — | — | US | disclosed |
| US-20240368177-A1 | 5-AMINO-6,8-DIHYDRO-1H-FURO[3,4-d]PYRROLO[3,2-b]PYRIDINE-2-CARBOXAMIDE DERIVATIVES AS MTA-COOPERATIVE INHIBITORS OF PRMT5 | BEIGENE SWITZERLAND GMBH (CH) | 2024-11-07 | — | — | US | disclosed |
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |
| US-7166614-B2 | Tetrahydropyranyl cyclopentyl tetrahydroisoquinoline modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-7166614-B2 | Tetrahydropyranyl cyclopentyl tetrahydroisoquinoline modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-6924251-B1 | Substituted benzoylcyclohexandiones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-02 | — | — | US | disclosed |
| US-20050079979-A1 | Substituted benzoylisoxazoles and the use thereof as herbicides | MULLER KLAUS-HELMUT (DE) | 2005-04-14 | — | — | US | disclosed |
| US-6838415-B1 | Substituted benzoylisoxazoles and the use thereof as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2005-01-04 | — | — | US | disclosed |
| US-20040248740-A1 | Substituted benzoylpyrazoles | MULLER KLAUS-HELMUT (DE) | 2004-12-09 | — | — | US | disclosed |
| US-6746989-B1 | HAVE STRONG HERBICIDAL ACTIVITY AND BROAD ACTIVITY SPECTRUM WHEN APPLIED TO SOIL AND ON ABOVE-GROUND PARTS OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-08 | — | — | US | disclosed |
| CN-1349532-A | Substituted benzoyl isoxazoles and their use as herbicides | BAYER AG (DE) | 2002-05-15 | — | — | CN | disclosed |
| CN-1310714-A | Substituted Benzoylcyclohexanediones | BAYER AG (DE) | 2001-08-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248740-A1 | Substituted benzoylpyrazoles | CYP1B1, CYP1A1, CYP2E1 | MRGPRX4 1376/4885CYP4F2 75/4885CYP4A11 96/4885 |
| US-20260132149-A1 | Bridged Cyclic 5-Amino-6,8-Dihydro-1H-Furo[3,4-D]Pyrrolo[3,2-B]Pyridine-2-Carboxamide Compounds, Compositions Thereof, and Methods of Treatment Therewith | MECP2, PRMT5, DNMT1 | MRGPRX4 3734/4885CYP4F2 3095/4885CYP4A11 2871/4885 |
| US-20240368177-A1 | 5-AMINO-6,8-DIHYDRO-1H-FURO[3,4-d]PYRROLO[3,2-b]PYRIDINE-2-CARBOXAMIDE DERIVATIVES AS MTA-COOPERATIVE INHIBITORS OF PRMT5 | PRMT5, PRMT6, PRMT1 | MRGPRX4 2766/4885CYP4F2 3695/4885CYP4A11 4621/4885 |
| US-20050079979-A1 | Substituted benzoylisoxazoles and the use thereof as herbicides | CYP4X1, DDT, GLRX3 | MRGPRX4 325/4885CYP4F2 44/4885CYP4A11 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.