Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 18/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004442 | 0.91 | FKBP1A (0.92) | FKBP1A | |
| SCHEMBL15048988 | 0.91 | FKBP1A (0.92) | FKBP1A | |
| SCHEMBL4679960 | 0.90 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL1776165 | 0.90 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL6317432 | 0.83 | FKBP1A (0.57) | FKBP1A | |
| SCHEMBL12311519 | 0.79 | FKBP1A (0.72) | FKBP1A | |
| SCHEMBL8587480 | 0.78 | FKBP1A (0.80) | FKBP1A | |
| SCHEMBL499268 | 0.78 | FKBP1A (0.80) | FKBP1A | |
| SCHEMBL6534225 | 0.78 | FKBP1A (0.60) | FKBP1A | |
| SCHEMBL10066851 | 0.78 | FKBP1A (0.92) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6544976-B1 | Treating disorders characterized by neuronal damage caused by disease or trauma, such as Parkinson's disease, Alzheimer's disease, stroke, multiple sclerosis, amyotrophic lateral sclerosis, diabetic neuropathy and Bell's palsy. | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-04-08 | — | — | US | disclosed |
| WO-2001004091-A1 | NEUROTROPHIC 2-AZETIDINECARBOXYLIC ACID DERIVATIVES, AND RELATED COMPOSITIONS AND METHODS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |