Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 18/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679960 | 1.00 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL15048988 | 0.96 | FKBP1A (0.92) | FKBP1A | |
| SCHEMBL2004442 | 0.96 | FKBP1A (0.92) | FKBP1A | |
| SCHEMBL7250340 | 0.90 | FKBP1A (0.82) | FKBP1A | |
| SCHEMBL499268 | 0.89 | FKBP1A (0.80) | FKBP1A | |
| SCHEMBL8587480 | 0.89 | FKBP1A (0.80) | FKBP1A | |
| SCHEMBL610524 | 0.88 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL26210430 | 0.88 | FKBP1A (0.78) | FKBP1A | |
| SCHEMBL5834032 | 0.88 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL18707755 | 0.85 | FKBP1A (0.74) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4242304-A2 | METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES | Warp Drive Bio, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| US-20220193242-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-23 | — | — | US | disclosed |
| EP-2794566-A1 | PIPECOLATE-DIKETOAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013091900-A1 | PIPECOLATE-DIKETOAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-06-27 | — | — | WO | disclosed |
| EP-2607352-A1 | Pipecolate-diketoamides for treatment of psychiatric disorders | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-06-26 | — | — | EP | disclosed |
| US-7943775-B2 | to detect amyloid deposits prior to aggregation into plaques; labeled bifunctional compound binds to target protein and to chaperone protein; Alzheimer's; 1-[4-(carboxymethoxy)phenyl]-3-(3,4-dimethoxy-phenyl)-1-propanyl-1-(3,3-dimethyl-1,2-dioxopentyl)-2-piperidinecarboxylate isomers bind differently | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-05-17 | — | — | US | disclosed |
| US-7943775-B2 | to detect amyloid deposits prior to aggregation into plaques; labeled bifunctional compound binds to target protein and to chaperone protein; Alzheimer's; 1-[4-(carboxymethoxy)phenyl]-3-(3,4-dimethoxy-phenyl)-1-propanyl-1-(3,3-dimethyl-1,2-dioxopentyl)-2-piperidinecarboxylate isomers bind differently | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-05-17 | — | — | US | disclosed |
| US-7943775-B2 | to detect amyloid deposits prior to aggregation into plaques; labeled bifunctional compound binds to target protein and to chaperone protein; Alzheimer's; 1-[4-(carboxymethoxy)phenyl]-3-(3,4-dimethoxy-phenyl)-1-propanyl-1-(3,3-dimethyl-1,2-dioxopentyl)-2-piperidinecarboxylate isomers bind differently | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-05-17 | — | — | US | disclosed |
| US-20090162858-A1 | Orthogonal chemical inducer of dimerization | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2009-06-25 | — | — | US | disclosed |
| US-20090162858-A1 | Orthogonal chemical inducer of dimerization | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2009-06-25 | — | — | US | disclosed |
| US-20080085238-A1 | Small Molecules for Imaging Protein-Protein Interactions | The Government of the United States of America as represented (US) | 2008-04-10 | — | — | US | disclosed |
| US-20080085238-A1 | Small Molecules for Imaging Protein-Protein Interactions | The Government of the United States of America as represented (US) | 2008-04-10 | — | — | US | disclosed |
| US-20080085238-A1 | Small Molecules for Imaging Protein-Protein Interactions | The Government of the United States of America as represented (US) | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085238-A1 | Small Molecules for Imaging Protein-Protein Interactions | HSPBP1, HSPA2, HSPA8 | FKBP1A 1547/4885 |
| US-20220193242-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | CD74, CD2BP2, SERPINB1 | FKBP1A 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.