Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250291 | 0.85 | HRH2 (0.43) | ALDH1A1MAPT | |
| SCHEMBL7248197 | 0.85 | KCNH2 (0.49) | MEN1KMT2AKCNH2ALDH1A1KDM4E | |
| SCHEMBL7251587 | 0.85 | ALDH1A1 (0.47) | MEN1KMT2AKCNH2ALDH1A1KDM4E | |
| SCHEMBL7249987 | 0.84 | L3MBTL1 (0.47) | MEN1KMT2AKCNH2ALDH1A1KDM4E | |
| SCHEMBL7244717 | 0.83 | MEN1 (0.51) | MEN1KMT2AKCNH2ALDH1A1KDM4E | |
| SCHEMBL7251528 | 0.83 | ALDH1A1 (0.49) | MEN1KMT2AKCNH2ALDH1A1KDM4E | |
| SCHEMBL6094907 | 0.83 | KCNH2 (0.52) | MEN1KMT2AKCNH2ALDH1A1KDM4E | |
| SCHEMBL6094912 | 0.83 | KCNH2 (0.52) | MEN1KMT2AKCNH2ALDH1A1KDM4E | |
| SCHEMBL7246413 | 0.83 | MEN1 (0.47) | MEN1KMT2AKCNH2ALDH1A1KDM4E | |
| SCHEMBL7242512 | 0.82 | KCNH2 (0.51) | MEN1KMT2AKCNH2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559162-B2 | Electrophysiological activity | ASTRAZENECA AB (SE) | 2003-05-06 | — | — | US | disclosed |