SCHEMBL725058

SCHEMBL725058

Nc1cccc(C=O)c1C=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
LMNA P02545 1/20 0.48
THRB P10828 1/20 0.48
BLM P54132 1/20 0.48
ERN1 O75460 4/20 0.41
ALDH1A1 P00352 5/20 0.41
TSHR P16473 3/20 0.39
TRIM24 O15164 2/20 0.39
TRIM33 Q9UPN9 2/20 0.39
CYP2A6 P11509 1/20 0.36
CYP3A4 P08684 3/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
HTT P42858 1/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
TLR2 O60603 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6899284 0.85 ALDH1A1 (0.48) TDP1MEN1KMT2ALMNATHRB
SCHEMBL547829 0.82 KMT2A (0.61) TDP1MEN1KMT2ALMNATHRB
SCHEMBL4127921 0.78 TDP1 (0.38) TDP1MEN1KMT2ALMNATHRB
SCHEMBL1655785 0.78 TDP1 (0.50) TDP1MEN1KMT2ALMNATHRB
SCHEMBL25505 0.77
SCHEMBL29365160 0.77
SCHEMBL29776700 0.77
SCHEMBL9658857 0.77 KMT2A (0.55) TDP1MEN1KMT2ALMNATHRB
SCHEMBL15453223 0.77 MEN1 (0.39) TDP1MEN1KMT2ALMNATHRB
SCHEMBL548691 0.75 KMT2A (0.52) TDP1MEN1KMT2ALMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1249270-C Palladium plating solution KOJIMA CHEMICALS CO LTD (JP) 2006-04-05 CN claimed
CN-1420947-A Palladium plating solution KOJIMA CHEMICALS CO LTD (JP) 2003-05-28 CN claimed
EP-4327878-A2 COMBINATION OF A CELL THERAPY AND AN IMMUNOMODULATORY COMPOUND Juno Therapeutics, Inc. (US) 2024-02-28 EP disclosed
EP-3076973-B1 COMBINATIONS OF HISTONE DEACETYLASE INHIBITORS AND IMMUNOMODULATORY DRUGS ACETYLON PHARMACEUTICALS INC (US) 2020-04-29 EP disclosed
EP-3622960-A1 NATURAL KILLER CELLS FROM PLACENTA Celularity, Inc. (US) 2020-03-18 EP disclosed
WO-2019068048-A1 PLACENTA-DERIVED INTERMEDIATE NATURAL KILLER (PINK) CELLS FOR TREATMENT OF GLIOBLASTOMA Celularity, Inc. (US) 2019-04-04 WO disclosed
WO-2019067792-A1 TUMOR SUPPRESSION USING HUMAN PLACENTA-DERIVED INTERMEDIATE NATURAL KILLER (PINK) CELLS IN COMBINATION WITH AN ANTIBODY Celularity, Inc. (US) 2019-04-04 WO disclosed
EP-2783692-B1 TUMOR SUPPRESSION USING HUMAN PLACENTAL PERFUSATE AND HUMAN PLACENTA-DERIVED INTERMEDIATE NATURAL KILLER CELLS CELULARITY INC (US) 2019-01-02 EP disclosed
US-20170296450-A1 METHODS AND MATERIALS FOR DELIVERING AGENTS TO HAIR, SKIN, OR NAILS SAFEWHITE, INC. (US) 2017-10-19 US disclosed
EP-3193815-A1 METHODS AND MATERIALS FOR DELIVERING AGENTS TO HAIR, SKIN, OR NAILS SafeWhite, Inc. (US) 2017-07-26 EP disclosed
EP-2608761-B1 METHODS AND MATERIALS FOR PROVIDING TEETH WITH A WHITE APPEARANCE SAFEWHITE INC (US) 2016-08-24 EP disclosed
CN-1249270-C Palladium plating solution KOJIMA CHEMICALS CO LTD (JP) 2006-04-05 CN disclosed
US-6984716-B2 Phosphorus-containing compound CHANG CHUN PLASTICS CO., LTD. (TW) 2006-01-10 US disclosed
US-20040077821-A1 Flame retarding resin composition CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-22 US disclosed
US-20040077825-A1 Phosphorus-containing compound CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-22 US disclosed
EP-1396559-A1 PALLADIUM PLATING SOLUTION Kojima Chemicals Co., Ltd (JP) 2004-03-10 EP disclosed
CN-1420947-A Palladium plating solution KOJIMA CHEMICALS CO LTD (JP) 2003-05-28 CN disclosed
CN-85107547-A Microchemiluminescent detection system 1987-04-15 CN disclosed
US-4291902-A PRESSURE- AND HEAT-SENSITIVE ELEMENTS; COPYING; COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1981-09-29 US disclosed
US-4191690-A COLOR FORMERS CIBA-GEIGY CORPORATION (US) 1980-03-04 US disclosed