Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | MC5R | P33032 | 1/20 | 0.43 |
| ▸ | MC3R | P41968 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7251520 | 0.80 | KMT2A (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9943392 | 0.79 | HPGD (0.47) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL17956980 | 0.79 | NPSR1 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9943325 | 0.78 | HPGD (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7253743 | 0.78 | MC5R (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL23973931 | 0.77 | YAP1 (0.55) | SMN1; SMN2ALDH1A1MDM2MAPTTSHR | |
| SCHEMBL17956969 | 0.75 | KMT2A (0.51) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9943348 | 0.75 | HPGD (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7256847 | 0.75 | MC4R (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL25208378 | 0.75 | YAP1 (0.71) | MEN1KMT2ASMN1; SMN2ALDH1A1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030195212-A1 | Novel melanocortin receptor agonists and antagonists | MELACURE THERAPEUTICS AB (SE) | 2003-10-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195212-A1 | Novel melanocortin receptor agonists and antagonists | MC1R, MC5R, MC4R | MEN1 1200/4885KMT2A 1399/4885SMN1; SMN2 4503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.