Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 14/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 13/20 | 0.45 |
| ▸ | TUBB | P07437 | 13/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 13/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 13/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 13/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 13/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 13/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 13/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 13/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 13/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 13/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 13/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 13/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 13/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725347 | 0.80 | TUBB4A (0.56) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL723973 | 0.77 | MEN1 (0.53) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL770174 | 0.76 | MEN1 (0.52) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL786749 | 0.76 | TUBB1 (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL723242 | 0.74 | EGFR (0.50) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4421760 | 0.74 | TUBB4A (0.58) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15135710 | 0.73 | MAOB (0.48) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3469479 | 0.73 | EGFR (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30603593 | 0.73 | TUBB4A (0.52) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL805056 | 0.73 | TUBB4A (0.52) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027481-A9 | COMPOUNDS FOR TREATMENT OF CANCER | GTX, INC. (US) | 2013-10-10 | — | — | WO | disclosed |
| EP-2608671-A1 | COMPOUNDS FOR TREATMENT OF CANCER | Gtx, Inc. (US) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012027481-A1 | COMPOUNDS FOR TREATMENT OF CANCER | GTX, INC. (US) | 2012-03-01 | — | — | WO | disclosed |