SCHEMBL723973

SCHEMBL723973

COc1cc(C(=O)c2c[nH]c(Nc3ccccc3)n2)cc(OC)c1OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
BRAF P15056 1/20 0.45
USP2 O75604 1/20 0.45
TUBB4A P04350 6/20 0.45
TUBB P07437 6/20 0.45
TUBA3C P0DPH7 6/20 0.45
TUBA1B P68363 6/20 0.45
TUBA4A P68366 6/20 0.45
TUBB4B P68371 6/20 0.45
TUBB3 Q13509 6/20 0.45
TUBB2A Q13885 6/20 0.45
TUBB8 Q3ZCM7 6/20 0.45
TUBA3E Q6PEY2 6/20 0.45
TUBA1A Q71U36 6/20 0.45
TUBA1C Q9BQE3 6/20 0.45
TUBB6 Q9BUF5 6/20 0.45
TUBB2B Q9BVA1 6/20 0.45
TUBB1 Q9H4B7 6/20 0.45
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL770174 0.99 MEN1 (0.52) MEN1KMT2ABRAFUSP2TUBB4A
SCHEMBL786505 0.83 TUBB1 (0.60) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL786597 0.83 TUBB1 (0.52) USP2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL725347 0.80 TUBB4A (0.56) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL25478528 0.79 TUBB1 (0.43) USP2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL19221052 0.78 TUBB1 (0.37) USP2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL19214630 0.77 MEN1 (0.53) MEN1KMT2ABRAFUSP2TUBB4A
SCHEMBL725066 0.77 TUBB1 (0.45) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL721918 0.77 HPGDS (0.54) MEN1KMT2A
SCHEMBL19221058 0.77 TUBB1 (0.41) USP2TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3793549-A1 COMPOUNDS FOR TREATMENT OF TRIPLE NEGATIVE BREAST CANCER AND OVARIAN CANCER University of Tennessee Research Foundation (US) 2021-03-24 EP claimed
EP-3793548-A1 COMPOUNDS FOR TREATMENT OF PANCREATIC CANCER University of Tennessee Research Foundation (US) 2021-03-24 EP claimed
WO-2021041744-A1 RYL BENZOYL IMIDAZOLE COMPOUNDS FOR THE TREATMENT OF LUNG CANCER UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2021-03-04 WO claimed
US-8822513-B2 Compounds for treatment of cancer GTX, INC. (US) 2014-09-02 US claimed
WO-2012027481-A9 COMPOUNDS FOR TREATMENT OF CANCER GTX, INC. (US) 2013-10-10 WO claimed
EP-2608671-A1 COMPOUNDS FOR TREATMENT OF CANCER Gtx, Inc. (US) 2013-07-03 EP claimed
US-20120071524-A1 COMPOUNDS FOR TREATMENT OF CANCER ONCTERNAL THERAPEUTICS, INC 2012-03-22 US claimed
WO-2012027481-A1 COMPOUNDS FOR TREATMENT OF CANCER GTX, INC. (US) 2012-03-01 WO claimed
US-20250188072-A1 COMPOUNDS FOR TREATMENT OF CANCER UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-06-12 US disclosed
CN-119548495-A Use of (substituted 1H-imidazol-4-yl) (3, 4, 5-trimethoxyphenyl) methanones for the treatment of coronaviruses 维鲁公司 2025-03-04 CN disclosed
EP-4504183-A1 METHODS OF TREATING INFLUENZA AND POXVIRUS VIRAL INFECTIONS Veru Inc. (US) 2025-02-12 EP disclosed
US-12187720-B2 Compounds for treatment of cancer UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-01-07 US disclosed
CN-118984703-A Methods of treating influenza and poxvirus infections 维鲁公司 2024-11-19 CN disclosed
US-20240180879-A1 METHODS OF TREATING INFLAMMATION VERU INC. (US) 2024-06-06 US disclosed
EP-2608671-A1 COMPOUNDS FOR TREATMENT OF CANCER Gtx, Inc. (US) 2013-07-03 EP disclosed
US-20120071524-A1 COMPOUNDS FOR TREATMENT OF CANCER ONCTERNAL THERAPEUTICS, INC 2012-03-22 US disclosed
US-20120071524-A1 COMPOUNDS FOR TREATMENT OF CANCER ONCTERNAL THERAPEUTICS, INC 2012-03-22 US disclosed
US-20120071524-A1 COMPOUNDS FOR TREATMENT OF CANCER ONCTERNAL THERAPEUTICS, INC 2012-03-22 US disclosed
WO-2012027481-A1 COMPOUNDS FOR TREATMENT OF CANCER GTX, INC. (US) 2012-03-01 WO disclosed
WO-2012027481-A1 COMPOUNDS FOR TREATMENT OF CANCER GTX, INC. (US) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12187720-B2 Compounds for treatment of cancer KLK3, BRDT, ACP3 MEN1 165/4885KMT2A 2242/4885BRAF 5/4885
US-20120071524-A1 COMPOUNDS FOR TREATMENT OF CANCER KLK3, BRDT, ACP3 MEN1 165/4885KMT2A 2242/4885BRAF 5/4885
US-20240180879-A1 METHODS OF TREATING INFLAMMATION IL1B, PYCARD, TUBB1 MEN1 4618/4885KMT2A 3898/4885BRAF 3091/4885
US-20250188072-A1 COMPOUNDS FOR TREATMENT OF CANCER KLK3, BRDT, ACP3 MEN1 165/4885KMT2A 2242/4885BRAF 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.