Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 16/20 | 0.69 |
| ▸ | SELE | P16581 | 16/20 | 0.69 |
| ▸ | VCAM1 | P19320 | 8/20 | 0.56 |
| ▸ | CCNC | P24863 | 3/20 | 0.52 |
| ▸ | CDK8 | P49336 | 3/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.50 |
| ▸ | CDK1 | P06493 | 3/20 | 0.50 |
| ▸ | PIM1 | P11309 | 3/20 | 0.50 |
| ▸ | PRKACA | P17612 | 3/20 | 0.50 |
| ▸ | CDK2 | P24941 | 3/20 | 0.50 |
| ▸ | FLT4 | P35916 | 3/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.50 |
| ▸ | GSK3A | P49840 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 3/20 | 0.50 |
| ▸ | PLK1 | P53350 | 3/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250679 | 0.86 | ICAM1 (0.66) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7054474 | 0.82 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7255481 | 0.81 | ICAM1 (0.69) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7797352 | 0.80 | ICAM1 (0.69) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7931907 | 0.79 | ICAM1 (0.72) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7855096 | 0.78 | CDK1 (0.54) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7797360 | 0.76 | ICAM1 (0.55) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7642734 | 0.75 | ICAM1 (0.64) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7846850 | 0.75 | ICAM1 (0.74) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7054697 | 0.74 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579882-B2 | Thieno(2,3-d)pyrimidine derivatives | ABBOTT LABORATORIES | 2003-06-17 | — | — | US | disclosed |
| US-20010020030-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ABBVIE INC. | 2001-09-06 | — | — | US | disclosed |
| EP-1090009-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999062908-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 1999-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020030-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ICAM1, VCAM1, EPCAM | ICAM1 1/4885SELE 16/4885VCAM1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.