Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 8/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.74 |
| ▸ | GRIA4 | P48058 | 12/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607084 | 1.00 | GRIA2 (0.74) | GRIA2KCNH2GRIA4KDM1A | |
| SCHEMBL7250835 | 1.00 | GRIA2 (0.74) | GRIA2KCNH2GRIA4KDM1A | |
| SCHEMBL7254117 | 0.89 | GRIA4 (0.64) | GRIA2KCNH2GRIA4 | |
| SCHEMBL14141327 | 0.85 | GRIA2 (0.73) | GRIA2KCNH2GRIA4KDM1A | |
| SCHEMBL4605918 | 0.85 | GRIA2 (0.73) | GRIA2KCNH2GRIA4KDM1A | |
| SCHEMBL4607295 | 0.85 | GRIA2 (0.73) | GRIA2KCNH2GRIA4KDM1A | |
| SCHEMBL4605831 | 0.85 | GRIA4 (0.55) | GRIA2KCNH2GRIA4 | |
| SCHEMBL4605833 | 0.85 | GRIA4 (0.55) | GRIA2KCNH2GRIA4 | |
| SCHEMBL5187367 | 0.85 | GRIA2 (1.00) | GRIA2KCNH2KDM1A | |
| SCHEMBL5187358 | 0.85 | GRIA2 (1.00) | GRIA2KCNH2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | claimed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | disclosed |