Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29869259 | 0.85 | KMT2A (0.69) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL7250664 | 0.85 | ALDH1A1 (0.73) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL7251382 | 0.82 | BMP1 (0.56) | KMT2AMEN1HCRTR1 | |
| SCHEMBL7849863 | 0.81 | MAPT (0.61) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL7850854 | 0.81 | MAPT (0.60) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL1231823 | 0.81 | MEN1 (0.78) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL1233360 | 0.81 | MEN1 (0.78) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL23417935 | 0.80 | ALDH1A1 (1.00) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL6643764 | 0.80 | MEN1 (0.76) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL30712556 | 0.79 | KDM4E (0.80) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030195212-A1 | Novel melanocortin receptor agonists and antagonists | MELACURE THERAPEUTICS AB (SE) | 2003-10-16 | — | — | US | claimed |
| EP-1254114-A2 | MELANOCORTIN RECEPTOR AGONISTS AND ANTAGONISTS | Melacure Therapeutics AB (SE) | 2002-11-06 | — | — | EP | claimed |
| WO-2001055106-A2 | NOVEL MELANOCORTIN RECEPTOR AGONISTS AND ANTAGONISTS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195212-A1 | Novel melanocortin receptor agonists and antagonists | MC1R, MC5R, MC4R | KDM4E 1977/4885ALDH1A1 2823/4885L3MBTL1 3846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.