SCHEMBL7252

SCHEMBL7252

Clc1ccc2ccccc2n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 3/20 0.58
NOS2 P35228 1/20 0.58
BACE1 P56817 1/20 0.58
CYP1A2 P05177 2/20 0.52
CA12 O43570 1/20 0.52
CA9 Q16790 1/20 0.52
TDP1 Q9NUW8 2/20 0.48
ALDH1A1 P00352 2/20 0.48
MAPT P10636 2/20 0.48
GLA P06280 1/20 0.48
HPGD P15428 1/20 0.48
ACHE P22303 1/20 0.48
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
KDM4E B2RXH2 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MGAM O43451 1/20 0.45
CNR2 P34972 1/20 0.44
AR P10275 2/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30168988 1.00 NCF1 (0.58) NCF1NOS2BACE1CYP1A2CA12
SCHEMBL14127304 1.00 NCF1 (0.58) NCF1NOS2BACE1CYP1A2CA12
SCHEMBL7429726 0.97 NCF1 (0.56) NCF1NOS2BACE1CYP1A2CA12
Hydrochloric Acid SCHEMBL3651493 0.97 NCF1 (0.56) NCF1NOS2BACE1CYP1A2CA12
SCHEMBL28744150 0.97 NCF1 (0.56) NCF1NOS2BACE1CYP1A2CA12
SCHEMBL516637 0.89 NCF1 (0.48) NCF1NOS2BACE1CYP1A2CA12
Quinoline SCHEMBL1168982 0.87 ALDH1A1 (0.68) NCF1NOS2BACE1CYP1A2CA12
Phosphoric Acid SCHEMBL29119725 0.87 NCF1 (0.47) NCF1NOS2BACE1CYP1A2CA12
Putrescine SCHEMBL5357478 0.85 NCF1 (0.50) NCF1NOS2BACE1CYP1A2CA12
SCHEMBL11657951 0.82 KDM4E (0.44) NCF1NOS2BACE1CYP1A2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4116 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865932-B Preparation method of benzothiophene sulfone compound with medicinal and fluorescent activity BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) 2026-05-26 CN claimed
CN-119285543-B Sulfonylation method of halogenated quinoline and aryl sulfonyl hydrazine 南京工业大学 2026-05-15 CN claimed
CN-121574682-A Adhesive for inhibiting metal coating from falling off, and preparation method and construction method thereof 无锡市宜刚耐火材料有限公司 2026-02-27 CN claimed
CN-119842078-A Polysulfone resin, preparation method thereof and polymer product 深圳市沃特新材料股份有限公司 2025-04-18 CN claimed
US-12245498-B2 Organoiridium complex for organic electroluminescent elements TANAKA KIKINZOKU KOGYO K.K. (JP) 2025-03-04 US claimed
CN-119395182-A Method for detecting 2-chloro-propanediol and 3-chloro-propanediol 上海应用技术大学 2025-02-07 CN claimed
CN-119320413-A Ionic iridium complex photosensitizer as well as preparation method and application thereof 南京工业大学 2025-01-17 CN claimed
CN-119285543-A Sulfonylation method of halogenated quinoline and aryl sulfonyl hydrazine 南京工业大学 2025-01-10 CN claimed
CN-119039356-A Fluoranthene group-containing deep red to near infrared iridium (III) complex, preparation method and application thereof 西安交通大学 2024-11-29 CN claimed
CN-116655530-B Zinc ion detection fluorescent probe compound and preparation method and application thereof 南京林业大学 2024-08-13 CN claimed
CN-86103115-A A kind of energy is anticancer, analgesic compound and method for making and purposes 1987-11-11 CN claimed
EP-0221947-A1 TRIAZOLYL QUINOLINE DERIVATIVES. ALKALOIDA VEGYESZETI GYAR (HU) 1987-05-20 EP claimed
EP-0205362-A1 Quinolyl glycinamide derivatives, process for their preparation and their pharmaceutical use as psychotropes SANOFI (FR) 1986-12-17 EP claimed
WO-1986006721-A1 TRIAZOLYL QUINOLINE DERIVATIVES ALKALOIDA VEGYÉSZETI GYÁR (HU) 1986-11-20 WO claimed
EP-0056766-B1 PROCESS FOR THE PREPARATION OF 4-AMINO-CHLOROQUINOLINES RHONE-POULENC SANTE (FR) 1984-05-16 EP claimed
US-4411820-A A GROUP 8 METAL COMPOUND, A HETEROAROMATIC NITROGEN COMPOUND, AND AN OXIDE OF URANIUM OR THORIUM GULF RESEARCH & DEVELOPMENT COMPANY (US) 1983-10-25 US claimed
US-4380632-A HYDROLYSIS OF THE CARBALKOXY DERIVATIVE BY WATER USING AN ACID CATALYST; PRESSURIZATION; DISTILLATION; NEUTRALIZATION; DECARBOXYLATION DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1983-04-19 US claimed
US-4331560-A NOBLE METAL COMPOUND AND A HETEROCYCLIC NITROGEN COMPOUND AS CATALYST SYSTEM GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-05-25 US claimed
US-4212937-A NITROGEN-CONTAINING HETEROCYCLIC BASE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-07-15 US claimed
US-4009087-A N-HETERO AROMATIC, AND SULFOALKYL OR SULFOARYL SULFIDE M&T CHEMICALS INC. (US) 1977-02-22 US claimed