SCHEMBL7252000

SCHEMBL7252000

CCCOC(C)COC=O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7250057 0.88 ADH1B (0.35) TDP1
SCHEMBL7254653 0.82
SCHEMBL7248301 0.81 TDP1 (0.31) TDP1
SCHEMBL148774 0.78 TDP1 (0.39) TDP1HSD17B10
SCHEMBL7254375 0.77 ALDH1A1 (0.32)
SCHEMBL7250184 0.77
SCHEMBL27946743 0.77 TDP1 (0.38) TDP1HSD17B10
SCHEMBL923828 0.75 TDP1 (0.41) TDP1HSD17B10
SCHEMBL28440440 0.75
SCHEMBL10456641 0.74 TDP1 (0.48) TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6602825-B1 Cyclization of an isocyanate with a thiourea and carbonic acid BASF AKTIENGESELLSCHAFT (DE) 2003-08-05 US disclosed