Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252160 | 1.00 | FURIN (0.49) | FURINHPGDMAPTRAB9APPARG | |
| SCHEMBL6346576 | 0.82 | CA9 (0.40) | FURINHPGDMAPTRAB9AKMT2A | |
| SCHEMBL6346578 | 0.82 | CA9 (0.40) | FURINHPGDMAPTRAB9AKMT2A | |
| SCHEMBL9411079 | 0.82 | CA9 (0.40) | FURINHPGDMAPTRAB9AKMT2A | |
| SCHEMBL8438349 | 0.81 | FURIN (0.52) | FURINHPGDMAPTRAB9APPARG | |
| SCHEMBL16255397 | 0.79 | FURIN (0.50) | FURINHPGDMAPTRAB9AKMT2A | |
| SCHEMBL2545564 | 0.75 | GAA (0.54) | FURINHPGDMAPTRAB9APPARG | |
| SCHEMBL754261 | 0.75 | GAA (0.54) | FURINHPGDMAPTRAB9APPARG | |
| SCHEMBL12360950 | 0.74 | CA9 (0.52) | FURINHPGDMAPTRAB9AKMT2A | |
| SCHEMBL14298196 | 0.74 | CA9 (0.52) | FURINHPGDMAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610731-B2 | Antiinflammatory | BRISTOL-MYERS SQUIBB COMPANY | 2003-08-26 | — | — | US | disclosed |