Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FURIN | P09958 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6346578 | 1.00 | CA9 (0.40) | CA9GFERPOLBCASP3SENP8 | |
| SCHEMBL6346576 | 1.00 | CA9 (0.40) | CA9GFERPOLBCASP3SENP8 | |
| SCHEMBL7252160 | 0.82 | FURIN (0.49) | CA9GFERPOLBCASP3SENP8 | |
| SCHEMBL7252164 | 0.82 | FURIN (0.49) | CA9GFERPOLBCASP3SENP8 | |
| SCHEMBL12360950 | 0.81 | CA9 (0.52) | CA9GFERPOLBCASP3SENP8 | |
| SCHEMBL14298196 | 0.81 | CA9 (0.52) | CA9GFERPOLBCASP3SENP8 | |
| Water SCHEMBL4312372 | 0.77 | LMNA (0.50) | CA9GFERPOLBCASP3SENP8 | |
| SCHEMBL5958167 | 0.75 | GAA (0.40) | SMN1; SMN2MAPTRAB9AKMT2AFURIN | |
| SCHEMBL5958164 | 0.75 | GAA (0.40) | SMN1; SMN2MAPTRAB9AKMT2AFURIN | |
| SCHEMBL3389005 | 0.75 | LMNA (0.39) | SMN1; SMN2MAPTRAB9ACYP1A2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581464-A1 | Ester derivatives and pharmaceutical compositions containing them | ZENECA LIMITED (GB) | 1994-02-02 | — | — | EP | claimed |
| EP-0581464-A1 | Ester derivatives and pharmaceutical compositions containing them | ZENECA LIMITED (GB) | 1994-02-02 | — | — | EP | disclosed |