Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598006 | 0.92 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3598004 | 0.92 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1KMT2APKM | |
| SCHEMBL10117993 | 0.92 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1KMT2APKM | |
| SCHEMBL2721206 | 0.90 | ALDH1A1 (0.65) | TSHRSMN1; SMN2ALDH1A1KMT2APKM | |
| Hydrochloric Acid SCHEMBL29094269 | 0.90 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3609489 | 0.90 | TSHR (0.64) | TSHRSMN1; SMN2ALDH1A1KMT2APKM | |
| SCHEMBL3006709 | 0.90 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1HDAC3HDAC1 | |
| SCHEMBL2755804 | 0.90 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL19321442 | 0.90 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL1720194 | 0.89 | ALDH1A1 (0.67) | TSHRSMN1; SMN2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000219-B2 | Method for treatment of isocyanate residue, and method for treatment of carbonate | MITSUI CHEMICALS, INC. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-20120271067-A1 | METHOD FOR TREATMENT OF ISOCYANATE RESIDUE, AND METHOD FOR TREATMENT OF CARBONATE | MITSUI CHEMICALS, INC. | 2012-10-25 | — | — | US | disclosed |
| US-6639101-B2 | Catalytic thermal decomposition of carbamates using silicates (clays, zeolites) as catalysts | REPSOL QUIMICA, S.A. (ES) | 2003-10-28 | — | — | US | disclosed |
| US-5138015-A | Reacting dialkyl carbonate with diamine to give urethane, thermally decomposing into diisocyanate, coverting into polyurethane in presence of Lewis acid and/or protonic acid | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0477376-A1 | PROCESS FOR PRODUCING POLYURETHANE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-01 | — | — | EP | disclosed |