Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | F13A1 | P00488 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29094269 | 0.98 | TSHR (0.59) | TSHRSMN1; SMN2CA1CA2ALDH1A1 | |
| SCHEMBL7252186 | 0.92 | TSHR (0.69) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL10117993 | 0.84 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3598004 | 0.84 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9089060 | 0.82 | TRPV1 (0.45) | TSHRCA1CA2KDM4EF13A1 | |
| SCHEMBL2721206 | 0.82 | ALDH1A1 (0.65) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL19321442 | 0.82 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3006709 | 0.82 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3609489 | 0.82 | TSHR (0.64) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL2755804 | 0.82 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250087-A | A kind of synthetic method of 4- isobutoxies benzylamine | 常州大学 | 2018-07-06 | — | — | CN | claimed |
| US-5494666-A | BETA-LACTAMASE INHIBITORS, ANTIBACTERIALS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | claimed |
| US-5464617-A | 1H-2,6a-diazacyclobut(cd)indene-6-carboxylic acid derivatives, antibiotics | HOFFMANN-LA ROCHE INC. (US) | 1995-11-07 | — | — | US | claimed |
| EP-0671401-A1 | Beta lactames | F. HOFFMANN-LA ROCHE AG (CH) | 1995-09-13 | — | — | EP | claimed |
| US-20260090547-A1 | BIO-INSECTICIDES FROM WASTE BIOMASS | UNIVERSITY OF DELAWARE (US) | 2026-04-02 | — | — | US | disclosed |
| WO-2025015272-A2 | BIO-INSECTICIDES FROM WASTE BIOMASS | UNIVERSITY OF DELAWARE (US) | 2025-01-16 | — | — | WO | disclosed |
| CN-108250087-A | A kind of synthetic method of 4- isobutoxies benzylamine | 常州大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-104961672-B | A kind of synthetic method of the tartrate of N (4 luorobenzyl) N (base of 1 methyl piperidine 4) N ' (4 isobutoxy benzyl) urea | 沈阳药科大学 | 2017-10-20 | — | — | CN | disclosed |
| US-20120015896-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2012-01-19 | — | — | US | disclosed |
| US-7754743-B2 | Heteroarylcarbamoylbenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20090018056-A1 | Heteroarylcarbamoylbenzene derivatives | MSD K.K. (JP) | 2009-01-15 | — | — | US | disclosed |
| US-7432287-B2 | Heteroarylcarbamoylbenzene derivative | BANYU PHARMECEUTICAL CO., LTD. (JP) | 2008-10-07 | — | — | US | disclosed |
| US-20060167053-A1 | Heteroarylcarbamoylbenzene derivative | MSD K.K. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1600442-A1 | HETEROARYLCARBAMOYLBENZENE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-5494666-A | BETA-LACTAMASE INHIBITORS, ANTIBACTERIALS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5464617-A | 1H-2,6a-diazacyclobut(cd)indene-6-carboxylic acid derivatives, antibiotics | HOFFMANN-LA ROCHE INC. (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0671401-A1 | Beta lactames | F. HOFFMANN-LA ROCHE AG (CH) | 1995-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260090547-A1 | BIO-INSECTICIDES FROM WASTE BIOMASS | PTMS, DDT, BCHE | TSHR 365/4885SMN1; SMN2 3070/4885CA1 3084/4885 |
| US-20120015896-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | PWWP2B, BRWD1, BAZ1A | TSHR 3833/4885SMN1; SMN2 3529/4885CA1 4760/4885 |
| US-20090018056-A1 | Heteroarylcarbamoylbenzene derivatives | GCK, GCKR, KHK | TSHR 2079/4885SMN1; SMN2 4432/4885CA1 2194/4885 |
| US-20060167053-A1 | Heteroarylcarbamoylbenzene derivative | GCK, GCKR, GALK1 | TSHR 3647/4885SMN1; SMN2 4329/4885CA1 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.