Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.76 |
| ▸ | POLB | P06746 | 6/20 | 0.72 |
| ▸ | TP53 | P04637 | 4/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.72 |
| ▸ | BLM | P54132 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252162 | 0.92 | MAPT (0.65) | MAPTPOLBTP53TDP1BLM | |
| SCHEMBL7252207 | 0.91 | MAPT (0.77) | MAPTPOLBTP53TDP1BLM | |
| SCHEMBL7255926 | 0.89 | MAPT (0.73) | MAPTPOLBTP53TDP1BLM | |
| SCHEMBL12700400 | 0.87 | MAPT (1.00) | MAPTPOLBTP53TDP1BLM | |
| SCHEMBL7252222 | 0.84 | MAPT (0.67) | MAPTPOLBTP53TDP1BLM | |
| SCHEMBL7252201 | 0.83 | MAPT (0.66) | MAPTPOLBTP53TDP1BLM | |
| SCHEMBL7253056 | 0.82 | ALDH1A1 (0.79) | MAPTPOLBTP53TDP1BLM | |
| SCHEMBL7252213 | 0.82 | ALDH1A1 (0.68) | MAPTPOLBTP53TDP1BLM | |
| SCHEMBL15411512 | 0.81 | GAA (0.98) | MAPTPOLBTP53TDP1BLM | |
| SCHEMBL15426021 | 0.81 | MAPT (0.90) | MAPTPOLBTP53TDP1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003010147-A1 | ACIDIC QUINOLONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-06 | — | — | WO | claimed |
| WO-2003010147-A1 | ACIDIC QUINOLONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-06 | — | — | WO | disclosed |