Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 5/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252207 | 0.92 | MAPT (0.77) | MAPTGAAKMT2ANPSR1TP53 | |
| SCHEMBL7252162 | 0.91 | MAPT (0.65) | MAPTGAAKMT2ANPSR1TP53 | |
| SCHEMBL7252168 | 0.89 | MAPT (0.57) | MAPTGAAKMT2ANPSR1TP53 | |
| SCHEMBL15410142 | 0.85 | MAPT (0.68) | MAPTGAAKMT2ANPSR1TP53 | |
| SCHEMBL7252736 | 0.83 | MAPT (0.76) | MAPTGAAKMT2ANPSR1TP53 | |
| SCHEMBL7252222 | 0.82 | MAPT (0.67) | MAPTGAAKMT2ANPSR1TP53 | |
| SCHEMBL7252752 | 0.81 | ALDH1A1 (0.64) | MAPTGAATP53TDP1SMN1; SMN2 | |
| SCHEMBL15409572 | 0.81 | TUBB4A (0.83) | MAPTGAAKMT2ANPSR1TP53 | |
| SCHEMBL15426023 | 0.81 | MAPT (0.75) | MAPTGAAKMT2ANPSR1TP53 | |
| SCHEMBL15410638 | 0.78 | MAPT (0.78) | MAPTGAAKMT2ANPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003010147-A1 | ACIDIC QUINOLONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-06 | — | — | WO | claimed |
| WO-2003010147-A1 | ACIDIC QUINOLONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-06 | — | — | WO | disclosed |