Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.61 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252878 | 1.00 | PPARG (0.61) | PPARGHSPB1MAPTNPSR1RAB9A | |
| SCHEMBL7039770 | 0.82 | PPARG (0.85) | PPARGHSPB1MAPTRAB9AMEN1 | |
| SCHEMBL7039776 | 0.82 | PPARG (0.85) | PPARGHSPB1MAPTRAB9AMEN1 | |
| SCHEMBL7040867 | 0.81 | PPARG (0.83) | PPARGMAPTRAB9AMEN1KMT2A | |
| Lithium Ion SCHEMBL7040861 | 0.76 | PPARG (1.00) | PPARGMAPTRAB9AMEN1KMT2A | |
| SCHEMBL7036261 | 0.75 | PPARG (0.82) | PPARGMAPTRAB9AMEN1KMT2A | |
| SCHEMBL11274403 | 0.73 | HSPB1 (0.73) | PPARGHSPB1MAPTNPSR1RAB9A | |
| SCHEMBL11162289 | 0.72 | HSPB1 (0.63) | PPARGHSPB1MAPTNPSR1RAB9A | |
| SCHEMBL1498294 | 0.71 | HSPB1 (0.67) | PPARGHSPB1MAPTNPSR1RAB9A | |
| SCHEMBL23926985 | 0.69 | HSPB1 (0.59) | PPARGHSPB1MAPTNPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004458-A1 | NEW COMPOUNDS | BIOVITRUM AB (SE) | 2003-01-16 | — | — | WO | claimed |