SCHEMBL7253011

SCHEMBL7253011

CC(N)(C#N)COc1csc(C(F)(F)F)c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3376870 0.76 NQO1 (0.39) ALDH1A1MAPT
SCHEMBL6012103 0.74 MAOB (0.44) ALDH1A1MAPT
SCHEMBL15670707 0.70 MAOB (0.40)
SCHEMBL3597416 0.69 AR (0.43)
SCHEMBL7253081 0.68 KDM4E (0.35) ALDH1A1MAPT
SCHEMBL3819632 0.67 ALDH3A1 (0.41) ALDH1A1MAPT
SCHEMBL3168510 0.65 AAK1 (0.42)
SCHEMBL31413934 0.65 AAK1 (0.42)
SCHEMBL31413935 0.65 CYP2D6 (0.44)
SCHEMBL21241117 0.64 MAPT (0.46) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003004474-A1 PESTICIDALLY ACTIVE AMINOACETONITRILES SYNGENTA PARTICIPATIONS AG (CH) 2003-01-16 WO disclosed