SCHEMBL7253176

SCHEMBL7253176

C=COC(COCC)OCCCC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28348882 0.93 TSHR (0.33) HPGDTSHR
SCHEMBL16149960 0.83 THRB (0.31)
SCHEMBL28131148 0.79 TSHR (0.33) TSHR
SCHEMBL4913690 0.78 HSD17B10 (0.38)
SCHEMBL17186653 0.76 TSHR (0.40) HPGDTSHR
SCHEMBL30981515 0.75
SCHEMBL28534846 0.74 TSHR (0.39) HPGDTSHR
SCHEMBL18512626 0.72 DNM1 (0.42) TSHR
SCHEMBL9502490 0.72 TSHR (0.42) HPGDTSHR
SCHEMBL4910614 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6642306-B1 In situ addition polymerization in the presence of azocarboxylic acid ester initiator ATOFINA (FR) 2003-11-04 US disclosed
EP-1192198-A1 PROCESS FOR MAKING GRAFT POLYOLS USING T-AMYL PEROXY FREE RADICAL INITIATOR BASF CORPORATION (US) 2002-04-03 EP disclosed
WO-2000059971-A1 PROCESS FOR MAKING GRAFT POLYOLS USING T-AMYL PEROXY FREE RADICAL INITIATOR BASF CORPORATION (DE) 2000-10-12 WO disclosed
US-5491252-A ISOCYANATE BLEND OF DIPHENYLMETHANE DIISOCYANTE/2,4-/ AND 4,4*-/, 3-RING OLIGOMER OF ABOVE AND N-RING OLIGOMER OF POLYMETHYLENEPOLYPHENYL POLYISOCYANATE, POLYHYDROXY POLYOLS AND TOLUENE DIISOCYANATE BASF CORPORATION (US) 1996-02-13 US disclosed
US-5459221-A Condensation polymerization of polyhydroxy compounds with diisocyanate compounds BASF CORPORATION (US) 1995-10-17 US disclosed
US-5436277-A Forming polyurethanes from diisocyanate blend BASF CORPORATION (US) 1995-07-25 US disclosed
US-4804771-A COUPLING AGENTS FOR GLASS FIBERS IN REINFORCED REACTION INJECTION MOLDING UNION CARBIDE CORPORATION (US) 1989-02-14 US disclosed
US-4797501-A POLYETHERSILOXANE COPOLYMERS AS STABILIZERS FOR POLYURETHANES UNION CARBIDE CORPORATION (US) 1989-01-10 US disclosed
US-4049636-A Thermally stable polyurethane elastomer useful in molding flexible automobile exterior body parts UNIROYAL, INC. (US) 1977-09-20 US disclosed
US-4041105-A Polyurethane elastomer derived from graft of ethylenically unsaturated monomer on polyalkylene ether glycol UNIROYAL, INC. (US) 1977-08-09 US disclosed