Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.47 |
| ▸ | PANK3 | Q9H999 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6698918 | 0.91 | MAPT (0.53) | MAPTSMN1; SMN2NAMPTMEN1TSHR | |
| SCHEMBL7258612 | 0.91 | MAPT (0.51) | MAPTSMN1; SMN2NAMPTMEN1TSHR | |
| SCHEMBL6695030 | 0.90 | MAPT (0.53) | MAPTSMN1; SMN2NAMPTMEN1TSHR | |
| SCHEMBL7253740 | 0.81 | MT-CO2 (0.55) | MAPTSMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL5459702 | 0.81 | MAPT (0.63) | MAPTSMN1; SMN2NAMPTMEN1TSHR | |
| SCHEMBL6697823 | 0.81 | MAPT (0.53) | MAPTSMN1; SMN2NAMPTMEN1TSHR | |
| SCHEMBL7253800 | 0.80 | ALDH1A1 (0.45) | MAPTSMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL7253746 | 0.80 | ALDH1A1 (0.45) | MAPTSMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL6551583 | 0.79 | MAPT (0.49) | MAPTSMN1; SMN2NAMPTMEN1TSHR | |
| SCHEMBL6695066 | 0.79 | MTTP (0.61) | MAPTSMN1; SMN2NAMPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048121-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |