⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259083 | 0.93 | — | — | |
| SCHEMBL5940600 | 0.88 | — | — | |
| SCHEMBL8154422 | 0.88 | — | — | |
| SCHEMBL8152565 | 0.85 | — | — | |
| SCHEMBL6780106 | 0.85 | — | — | |
| SCHEMBL7258099 | 0.82 | — | — | |
| SCHEMBL8154174 | 0.82 | ALDH1A1 (0.43) | — | |
| SCHEMBL5906869 | 0.79 | ALDH1A1 (0.40) | — | |
| SCHEMBL7254850 | 0.78 | — | — | |
| SCHEMBL7257430 | 0.78 | NPC1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772439-B1 | Novel antibiotic compounds and antibiotic compositions comprising said compounds for inhibiting gram positive bacteria and mycoplasma cells. | UNIV MASSACHUSETTS MEDICAL (US) | 2000-10-04 | — | — | EP | claimed |
| EP-0772439-A4 | NOVEL ANTIBIOTIC COMPOUNDS AND METHODS TO TREAT GRAM-POSITIVE BACTERIAL AND MYCOPLASMAL INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-01-07 | — | — | EP | claimed |
| EP-0772439-A1 | NOVEL ANTIBIOTIC COMPOUNDS AND METHODS TO TREAT GRAM-POSITIVE BACTERIAL AND MYCOPLASMAL INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-05-14 | — | — | EP | claimed |
| US-5516905-A | ENZYME INHIBITORS OF DNA POLYMERASE FOR BACTERICIDES | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-05-14 | — | — | US | claimed |
| WO-1996006614-A1 | NOVEL ANTIBIOTIC COMPOUNDS AND METHODS TO TREAT GRAM-POSITIVE BACTERIAL AND MYCOPLASMAL INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-03-07 | — | — | WO | claimed |
| WO-2003053959-A1 | HETEROCYCLYLAMINO CARBONYLURACILS | BAYER HEALTHCARE AG (DE) | 2003-07-03 | — | — | WO | disclosed |
| EP-0772439-B1 | Novel antibiotic compounds and antibiotic compositions comprising said compounds for inhibiting gram positive bacteria and mycoplasma cells. | UNIV MASSACHUSETTS MEDICAL (US) | 2000-10-04 | — | — | EP | disclosed |
| EP-0772439-A4 | NOVEL ANTIBIOTIC COMPOUNDS AND METHODS TO TREAT GRAM-POSITIVE BACTERIAL AND MYCOPLASMAL INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0772439-A1 | NOVEL ANTIBIOTIC COMPOUNDS AND METHODS TO TREAT GRAM-POSITIVE BACTERIAL AND MYCOPLASMAL INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-05-14 | — | — | EP | disclosed |
| US-5516905-A | ENZYME INHIBITORS OF DNA POLYMERASE FOR BACTERICIDES | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-05-14 | — | — | US | disclosed |
| WO-1996006614-A1 | NOVEL ANTIBIOTIC COMPOUNDS AND METHODS TO TREAT GRAM-POSITIVE BACTERIAL AND MYCOPLASMAL INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-03-07 | — | — | WO | disclosed |