Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154422 | 0.81 | — | — | |
| SCHEMBL7263989 | 0.80 | KDM4E (0.44) | NPC1RAB9AALDH1A1MEN1MAPT | |
| SCHEMBL8154174 | 0.80 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1MEN1MAPT | |
| SCHEMBL7258099 | 0.79 | — | — | |
| SCHEMBL7253779 | 0.78 | — | — | |
| SCHEMBL5940600 | 0.78 | — | — | |
| SCHEMBL8152565 | 0.78 | — | — | |
| SCHEMBL7259083 | 0.77 | — | — | |
| SCHEMBL6780106 | 0.76 | — | — | |
| SCHEMBL7264499 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003053959-A1 | HETEROCYCLYLAMINO CARBONYLURACILS | BAYER HEALTHCARE AG (DE) | 2003-07-03 | — | — | WO | disclosed |