Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407216 | 0.92 | PDE5A (0.48) | PDE5APDE6C | |
| SCHEMBL7254113 | 0.87 | PDE5A (0.59) | PDE5APDE6C | |
| SCHEMBL6407209 | 0.79 | PDE5A (0.61) | PDE5APDE6C | |
| SCHEMBL6407107 | 0.70 | PDE5A (0.57) | PDE5APDE6C | |
| SCHEMBL7254118 | 0.64 | KCNH2 (0.34) | — | |
| SCHEMBL6407022 | 0.62 | PDE5A (0.78) | PDE5A | |
| SCHEMBL6407036 | 0.61 | PDE5A (0.81) | PDE5A | |
| SCHEMBL6407728 | 0.61 | PDE5A (0.83) | PDE5A | |
| SCHEMBL1891581 | 0.61 | PDE5A (0.83) | PDE5A | |
| SCHEMBL1921643 | 0.60 | KMT2A (0.69) | PDE5APDE6C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635638-B2 | Treatment of sexual dysfunction, cardiovascular system disorders | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-10-21 | — | — | US | disclosed |