Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258232 | 0.95 | HRH4 (0.34) | MAOA | |
| SCHEMBL7259716 | 0.93 | HRH4 (0.36) | MAOA | |
| SCHEMBL5322896 | 0.78 | HRH4 (0.32) | — | |
| SCHEMBL7260073 | 0.73 | SIGMAR1 (0.32) | — | |
| Homohistamine SCHEMBL1073990 | 0.71 | — | — | |
| SCHEMBL6163941 | 0.71 | — | — | |
| SCHEMBL1260121 | 0.71 | — | — | |
| SCHEMBL10929671 | 0.71 | — | — | |
| SCHEMBL1258619 | 0.69 | TLR7 (0.33) | — | |
| SCHEMBL469143 | 0.69 | KCNH2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003011856-A1 | AMINOALKYLIMIDAZOLE DERIVATIVES PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2003-02-13 | — | — | WO | claimed |
| WO-2003011856-A1 | AMINOALKYLIMIDAZOLE DERIVATIVES PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2003-02-13 | — | — | WO | disclosed |