Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 6/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260911 | 0.87 | TP53 (0.61) | AGTR1AGTR2CNR1CNR2TP53 | |
| SCHEMBL7256425 | 0.78 | MAPT (0.52) | AGTR1AGTR2CNR1CNR2TP53 | |
| SCHEMBL7257420 | 0.77 | MAPT (0.60) | AGTR1AGTR2LMNATP53SMN1; SMN2 | |
| SCHEMBL15685952 | 0.74 | LMNA (1.00) | LMNATP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15568225 | 0.74 | LMNA (0.76) | CNR2LMNATP53SMN1; SMN2MEN1 | |
| SCHEMBL228889 | 0.73 | LMNA (0.90) | LMNATP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8320573 | 0.73 | TP53 (0.60) | AGTR1AGTR2CNR1CNR2LMNA | |
| SCHEMBL17380973 | 0.72 | POLB (0.58) | AGTR1AGTR2LMNATP53SMN1; SMN2 | |
| SCHEMBL8393405 | 0.71 | PPARG (0.84) | AGTR1AGTR2PPARG | |
| SCHEMBL541192 | 0.71 | MAPK1 (0.50) | AGTR1AGTR2LMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003011835-A1 | BENZIMIDAZOLYLALKYL-ARYL(ALKAN) OIC ACID DERIVATIVES AND THEIR USE AS ANTIHYPERGLYCAEMICS | MERCK PATENT GMBH (DE) | 2003-02-13 | — | — | WO | disclosed |