Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254710 | 0.90 | KCNA5 (0.41) | KCNA5ADRB2HTR1AKDM4AIDO1 | |
| SCHEMBL7259200 | 0.88 | KCNA5 (0.46) | KCNA5ADRB2HTR1AKDM4AIDO1 | |
| SCHEMBL7260153 | 0.82 | KCNA5 (0.46) | KCNA5ADRB2HTR1AKDM4AIDO1 | |
| SCHEMBL7257917 | 0.79 | KCNA5 (0.43) | KCNA5ADRB2HTR1AKDM4AALDH1A1 | |
| SCHEMBL11227054 | 0.78 | L3MBTL1 (0.54) | KCNA5KDM4AALDH1A1NPSR1ALOX15 | |
| SCHEMBL7260039 | 0.78 | ADRB2 (0.47) | KCNA5ADRB2HTR1AKDM4AALDH1A1 | |
| SCHEMBL3417084 | 0.77 | HPGD (0.60) | ALDH1A1NPSR1MEN1KMT2AITGA4 | |
| SCHEMBL8018113 | 0.76 | KCNA5 (0.56) | KCNA5KDM4AIDO1MEN1KMT2A | |
| SCHEMBL30159605 | 0.76 | KCNA5 (0.56) | KCNA5KDM4AIDO1MEN1KMT2A | |
| SCHEMBL26973982 | 0.76 | KCNA5 (0.47) | KCNA5ADRB2HTR1AKDM4AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003011222-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2003-02-13 | — | — | WO | disclosed |