Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088408 | 0.84 | PIM1 (0.46) | PIM1PIM2MAOAHRH3ADAMTS4 | |
| SCHEMBL7085848 | 0.77 | PIM1 (0.45) | PIM1PIM2MAOAHRH3ADAMTS4 | |
| SCHEMBL7134911 | 0.76 | PIM1 (0.36) | PIM1PIM2MAOAHRH3ADAMTS4 | |
| SCHEMBL7090634 | 0.74 | PIM1 (0.38) | PIM1PIM2MAOAHRH3ADAMTS4 | |
| SCHEMBL7089641 | 0.74 | PIM1 (0.38) | PIM1PIM2MAOAHRH3ADAMTS4 | |
| SCHEMBL10901812 | 0.70 | MAOA (0.43) | PIM1PIM2MAOAHRH3SLC6A3 | |
| SCHEMBL7088186 | 0.70 | PIM1 (0.34) | PIM1PIM2MAOAHRH3ADAMTS4 | |
| SCHEMBL7085825 | 0.70 | PIM1 (0.34) | PIM1PIM2MAOAHRH3ADAMTS4 | |
| SCHEMBL7091719 | 0.70 | PIM1 (0.34) | PIM1PIM2MAOAHRH3ADAMTS4 | |
| SCHEMBL7132800 | 0.69 | HRH3 (0.33) | PIM1PIM2MAOAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003011848-A1 | BENZOHETEROCYCLES AS LIPOXYGENASE INHITIBORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-02-13 | — | — | WO | disclosed |