Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 6/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615671 | 0.77 | ACHE (0.53) | MAOBBCHEACHE | |
| SCHEMBL7254338 | 0.77 | PIM1 (0.46) | PIM1PIM2MAOAHRH3MAOB | |
| SCHEMBL6617421 | 0.76 | CYP2A6 (0.48) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL7088408 | 0.75 | PIM1 (0.46) | PIM1PIM2MAOAHRH3MAOB | |
| SCHEMBL9315699 | 0.73 | PIM1 (0.44) | PIM1PIM2MAOAHRH3MAOB | |
| SCHEMBL10901812 | 0.72 | MAOA (0.43) | PIM1PIM2MAOAHRH3BCHE | |
| SCHEMBL28730836 | 0.71 | HTR1A (0.49) | FFAR1 | |
| SCHEMBL29576060 | 0.71 | HTR1A (0.49) | FFAR1 | |
| SCHEMBL28730839 | 0.71 | HTR1A (0.49) | FFAR1 | |
| SCHEMBL7134911 | 0.68 | PIM1 (0.36) | PIM1PIM2MAOAHRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055084-A1 | Pharmaceutical compounds and methods of use thereof | MILLENNIUM PHARMACEUTICAL, INC. | 2003-03-20 | — | — | US | disclosed |
| WO-2003011848-A1 | BENZOHETEROCYCLES AS LIPOXYGENASE INHITIBORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055084-A1 | Pharmaceutical compounds and methods of use thereof | CYP3A5, DHPS, CYP3A43 | PIM1 944/4885PIM2 1096/4885MAOA 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.