Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | ITK | Q08881 | 1/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29533596 | 0.88 | KDM4E (0.68) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL2330779 | 0.88 | KDM4E (0.68) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL29507671 | 0.82 | KIF11 (0.61) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL1517851 | 0.82 | KIF11 (0.61) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6009651 | 0.79 | KDM4E (0.59) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL1181326 | 0.79 | KDM4E (0.79) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL29670412 | 0.79 | KDM4E (0.79) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL30115280 | 0.79 | KDM4E (0.79) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL27218939 | 0.78 | KDM4E (0.51) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL7250494 | 0.78 | KDM4E (0.55) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030040538-A1 | Novel substituted tricyclic compounds | ASAHI-KASEI KABUSHIKI KAISHA (JP) | 2003-02-27 | — | — | US | disclosed |
| EP-1238973-A1 | NOVEL SUBSTITUTED TRICYCLIC COMPOUNDS | Asahi Kasei Kabushiki Kaisha (JP) | 2002-09-11 | — | — | EP | disclosed |
| CN-1126473-A | Carbazole derivatives with 17,20-lyase-inhibiting activity | GLAXO GROUP LTD (GB) | 1996-07-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040538-A1 | Novel substituted tricyclic compounds | CPT1A, CBR1, NR1H3 | ALDH1A1 1241/4885MEN1 4144/4885KMT2A 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.