SCHEMBL29533596

SCHEMBL29533596

COc1ccc2c(c1)[nH]c1cc(OC)ccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.68
ALDH1A1 P00352 7/20 0.68
HSD17B10 Q99714 5/20 0.68
MAPT P10636 4/20 0.68
KMT2A Q03164 3/20 0.68
MEN1 O00255 2/20 0.68
GFER P55789 2/20 0.68
TSHR P16473 1/20 0.68
HPGD P15428 5/20 0.62
RXFP1 Q9HBX9 1/20 0.61
DYRK1A Q13627 5/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
ADRA2A P08913 2/20 0.59
ADRA2B P18089 2/20 0.59
ADRA2C P18825 2/20 0.59
HTR7 P34969 2/20 0.59
NISCH Q9Y2I1 2/20 0.59
DYRK3 O43781 1/20 0.59
CCNT1 O60563 1/20 0.59
CCNB2 O95067 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2330779 1.00 KDM4E (0.68) KDM4EALDH1A1HSD17B10MAPTKMT2A
SCHEMBL6009651 0.90 KDM4E (0.59) KDM4EALDH1A1HSD17B10MAPTKMT2A
SCHEMBL29670412 0.90 KDM4E (0.79) KDM4EALDH1A1HSD17B10MAPTKMT2A
SCHEMBL30115280 0.90 KDM4E (0.79) KDM4EALDH1A1HSD17B10MAPTKMT2A
SCHEMBL1181326 0.90 KDM4E (0.79) KDM4EALDH1A1HSD17B10MAPTKMT2A
SCHEMBL7250494 0.88 KDM4E (0.55) KDM4EALDH1A1HSD17B10MAPTKMT2A
SCHEMBL10165568 0.88 CDK4 (0.61) KDM4EALDH1A1HSD17B10MAPTKMT2A
SCHEMBL7254385 0.88 ALDH1A1 (0.57) KDM4EALDH1A1HSD17B10MAPTKMT2A
SCHEMBL18487324 0.87 ALDH1A1 (0.53) KDM4EALDH1A1HSD17B10MAPTKMT2A
7-Methoxy-3-Methylcarbazole SCHEMBL602038 0.85 KDM4E (0.67) KDM4EALDH1A1HSD17B10MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372261-B Method for preparing 1-bromo/chloro carbazole and derivatives thereof 中国科学院兰州化学物理研究所 2023-06-27 CN claimed
CN-113943300-B Preparation method and application of 2, 7-dimethoxycarbazole fused compound 沈阳药科大学 2023-02-10 CN claimed
EP-4025643-A1 THERMOPLASTIC MOLDING COMPOSITIONS THAT RESIST HEAT BASF SE (DE) 2022-07-13 EP claimed
CN-113620964-B Substituted calixazole derivatives, and synthetic method and application thereof 沈阳药科大学 2022-07-01 CN claimed
CN-114341266-A Heat-resistant thermoplastic moulding materials 巴斯夫欧洲公司 2022-04-12 CN claimed
CN-115557881-B Organic micromolecular hole transport material, synthesis method and application thereof 南京理工大学 2024-09-03 CN disclosed
CN-113372261-B Method for preparing 1-bromo/chloro carbazole and derivatives thereof 中国科学院兰州化学物理研究所 2023-06-27 CN disclosed
CN-113943300-B Preparation method and application of 2, 7-dimethoxycarbazole fused compound 沈阳药科大学 2023-02-10 CN disclosed
CN-113943300-B Preparation method and application of 2, 7-dimethoxycarbazole fused compound 沈阳药科大学 2023-02-10 CN disclosed
CN-113943300-B Preparation method and application of 2, 7-dimethoxycarbazole fused compound 沈阳药科大学 2023-02-10 CN disclosed
CN-115557881-A Organic small molecule hole transport material, synthesis method and application thereof 南京理工大学 2023-01-03 CN disclosed
CN-113620964-B Substituted calixazole derivatives, and synthetic method and application thereof 沈阳药科大学 2022-07-01 CN disclosed
CN-114478555-A Substituted calix [4] carbazole derivative and synthesis method and application thereof 沈阳药科大学 2022-05-13 CN disclosed
CN-114341266-A Heat-resistant thermoplastic moulding materials 巴斯夫欧洲公司 2022-04-12 CN disclosed