Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 6/20 | 0.56 |
| ▸ | HINT1 | P49773 | 3/20 | 0.53 |
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | NT5E | P21589 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254452 | 1.00 | TYMP (0.56) | TYMPHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL6838999 | 0.94 | TYMP (0.59) | TYMPHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL7253951 | 0.87 | TYMP (0.49) | TYMPHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL7253950 | 0.87 | TYMP (0.49) | TYMPHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL6869098 | 0.85 | TYMP (0.77) | TYMPHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL1904550 | 0.85 | TYMP (0.76) | TYMPHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL10904155 | 0.85 | TYMP (0.76) | TYMPHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL646778 | 0.84 | HINT1 (0.54) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL4370987 | 0.83 | HINT1 (0.55) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL34927 | 0.82 | TYMP (0.64) | TYMPHINT1GSK3ARPS6KA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051881-A1 | SUBSTITUTED PURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS BY SOLID-PHASE COMBINATORIAL STRATEGIES | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |