Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257465 | 0.76 | TSHR (0.40) | ALDH1A1 | |
| SCHEMBL7667553 | 0.76 | SMN1; SMN2 (0.37) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL7667545 | 0.76 | SMN1; SMN2 (0.37) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL9651906 | 0.76 | SMN1; SMN2 (0.37) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL17087575 | 0.74 | ECE1 (0.32) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL25209042 | 0.72 | — | — | |
| SCHEMBL8618205 | 0.72 | CYP1A2 (0.34) | FFAR3SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25268194 | 0.72 | — | — | |
| SCHEMBL2710441 | 0.72 | — | — | |
| SCHEMBL4180706 | 0.71 | PGD (0.33) | SLC22A6CACNA2D1CACNB3CACNA1CPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051862-A1 | PROCESS FOR THE PREPARATION OF PYRANONE DERIVATIVES | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | disclosed |