Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | KIT | P10721 | 3/20 | 0.53 |
| ▸ | CTSV | O60911 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | NEK2 | P51955 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7251681 | 0.87 | CTSV (0.59) | CTSVCTSLHRH3MAOASMN1; SMN2 | |
| SCHEMBL7256537 | 0.80 | MAOA (0.49) | KITFLT3HRH3MAOASMN1; SMN2 | |
| SCHEMBL7256169 | 0.77 | CTSV (0.66) | CTSVCTSLFLT3MAOASMN1; SMN2 | |
| SCHEMBL7253632 | 0.77 | CTSV (0.66) | CTSVCTSLMAOANPC1TP53 | |
| SCHEMBL25634007 | 0.77 | MCHR1 (0.61) | MCHR1CTSVCTSLHRH3MAOA | |
| SCHEMBL14422827 | 0.77 | CTSV (0.83) | CTSVCTSLMAOASMN1; SMN2GABRA1 | |
| SCHEMBL1181539 | 0.76 | CTSV (0.64) | CTSVCTSLMAOARAB9ASMN1; SMN2 | |
| SCHEMBL7255064 | 0.76 | MAOA (0.64) | CTSVCTSLMAOANPC1RAB9A | |
| SCHEMBL7256768 | 0.76 | CTSV (0.57) | CTSVCTSLHRH3MAOASMN1; SMN2 | |
| SCHEMBL18171380 | 0.75 | KIT (0.86) | KITFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030040538-A1 | Novel substituted tricyclic compounds | ASAHI-KASEI KABUSHIKI KAISHA (JP) | 2003-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040538-A1 | Novel substituted tricyclic compounds | CPT1A, CBR1, NR1H3 | MCHR1 1164/4885KIT 4677/4885CTSV 3898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.